Table 2.
Somatic point mutations and structural variations in the HCC1954 and HCC1954BL genomes
| Somatic variations | HCC1954 | HCC1954BL |
|---|---|---|
| N (%) | N (%) | |
| Point mutations | 274 (100) | 173 (100) |
| Coding | 64 (23.36) | 30 (17.3) |
| Nonsense | 2 (0.73) | 3 (1.7) |
| Missense | 45 (16.42) | 15 (8.7) |
| Synonymous | 17 (6.20) | 12 (6.9) |
| Non-coding | 14 (5.11) | 15 (8.7) |
| UTR | 13 (4.74) | 13 (7.5) |
| ncRNA | 1 (0.36) | 2 (1.2) |
| miRNA | 0 (0) | 0 (0) |
| Intronic | 179 (65.33) | 114 (65.9) |
| Splice site | 0 (0) | 0 (0) |
| Other intronic | 179 (65.33) | 114 (65.9) |
| Intergenic | 17 (6.20) | 14 (8.1) |
| Structural variations | 94 (100) | 4 (100) |
| Interchromosomal | 49 (52.1) | 0 (0) |
| Intrachromosomal | 45 (47.9) | 4 (100) |
| Deletions | 30 (31.9) | 2 (50.0) |
| Inversions | 11 (11.7) | 2 (50.0) |
| Duplications | 4 (4.3) | 0 (0) |
UTR = untranslated region, ncRNA = non-coding RNA.