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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Neuroimage. 2011 May 14;57(3):918–927. doi: 10.1016/j.neuroimage.2011.05.023

Table 1.

Population demographics, cognitive test scores and abnormality scores computed by the classifier

TD Controls ASD patients T-statistic Group-
comparison

Number of
subjects
30
(14M, 16F)
45 (13 LI+, 32 LI−)
(42M, 3F)
- -
Age 10.3±2.5 10.5±2.5 0.35 0.73
SRS$ 44.2±7.4 78.2±10.5 16.1 <0.001
SCQ# 3.5±2.7 19.3±4.9 17.7 <0.001
CELF-4@ 108.1±11.3 92.7±16.9 −4.7 <0.001
CELF-4 (LI−) 100.8±10.7 −2.6 <0.012
CELF-4(LI+) 72.8±12.2 −8.8 <0.001

Abnormality
score*
0.22±0.52 −0.46±0.39 −5.9 <0.001
$

Social responsiveness scale (SRS) SRS score is a standard socio-psychological biomarker indicating social impairments. It was only measured for 44/45 ASD and 29/30 TD.

#

Social Communications Questionnaire (SCQ) evaluates social functioning and communication skills based on a questionnaire.

@

Clinical Evaluation of Language Fundamentals-edition 4 (CELF-4) score is a marker of language impairment in ASD. Therefore it is highly significant in TD vs. LI+ and less so in TD vs LI−.

*

The abnormality score is computed from the proposed classification technique using the LOO validation.