Table 1.
TD Controls | ASD patients | T-statistic | Group- comparison |
|
---|---|---|---|---|
Number of subjects |
30 (14M, 16F) |
45 (13 LI+, 32 LI−) (42M, 3F) |
- | - |
Age | 10.3±2.5 | 10.5±2.5 | 0.35 | 0.73 |
SRS$ | 44.2±7.4 | 78.2±10.5 | 16.1 | <0.001 |
SCQ# | 3.5±2.7 | 19.3±4.9 | 17.7 | <0.001 |
CELF-4@ | 108.1±11.3 | 92.7±16.9 | −4.7 | <0.001 |
CELF-4 (LI−) | ” | 100.8±10.7 | −2.6 | <0.012 |
CELF-4(LI+) | ” | 72.8±12.2 | −8.8 | <0.001 |
| ||||
Abnormality score* |
0.22±0.52 | −0.46±0.39 | −5.9 | <0.001 |
Social responsiveness scale (SRS) SRS score is a standard socio-psychological biomarker indicating social impairments. It was only measured for 44/45 ASD and 29/30 TD.
Social Communications Questionnaire (SCQ) evaluates social functioning and communication skills based on a questionnaire.
Clinical Evaluation of Language Fundamentals-edition 4 (CELF-4) score is a marker of language impairment in ASD. Therefore it is highly significant in TD vs. LI+ and less so in TD vs LI−.
The abnormality score is computed from the proposed classification technique using the LOO validation.