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. Author manuscript; available in PMC: 2011 Aug 8.
Published in final edited form as: Eur J Pharmacol. 2009 Nov 18;628(1-3):187–194. doi: 10.1016/j.ejphar.2009.11.029

Fig. 5.

Fig. 5

m-3M3FBS significantly decreased IL. Membrane potential was stepped from −80 to +50mV in 10mV increments from a holding potential of −80mV in (A) control and (B) in the presence of m-3M3FBS (10μM). (C) Representative traces where ramp depolarizations were applied from −80mV to +80mV over 500ms every 1 minute in control (a), m-3M3FBS (b), and washout (c). m-3M3FBS decreased peak ILVA (dashed line at −40mV and IL (vertical solid line at 0mV). (D) Summary of I-V relationships in control (○) and m-3M3FBS (●). m-3M3FBS (10μM) significantly decreased IL (n=7) but not ILVA.