The amount of endostar in tissues following a single injection of endostar-loaded PEG-PLGA, PLGA nanoparticles, and endostar. The left three bands were from the endostar-loaded PEG-PLGA nanoparticle group, the middle three ones from the PLGA nanoparticle group, and the right ones from the endostar group. Endostar was not detectable in the endostar, endostar-loaded PLGA, or PEG-PLGA microsphere groups.
Note: *Significantly different from PEG-PLGA nanoparticles (P < 0.05).
Abbreviations: PLGA, poly(DL-lactide-co-glycolide); PEG-PLGA, poly(ethylene glycol) modified poly(DL-lactide-co-glycolide).