Table 4.
Correspondence of our SBP linkage finding with other studies on chromosome 6q
Population | Trait | Chromosomal location | Marker region implicated | Position cM (Marshfield map) | LOD score | Reference |
---|---|---|---|---|---|---|
Mexican-Americans | SBP | 6q12 | D6S1053 | 080 | 2.2 | Rutherford et al., 2007 [46] |
Dutch families | DBP | 6q14.1 | D6S1031 | 089 | 2.5 | Allayee et al. 2001 [45] |
White families | SBP | 6q14.1 | D6S1031 | 089 | 3.3 | Hunt et al., 2002 [44] |
Present study | SBP | 6q14.1 | D6S1031 | 089 | 3.6 | Puppala et al. |
White families (Americans) | SBP | 6q23.3 – 6q24.2 | D6S1009-D6S1003 | 138–144 | 0.0001a | Krushkal et al., 1999 [47] |
Nigerian families | SBP | 6q26 | D6S1277 | 173 | 2.9 | Adeyemo et al., 2005 [13] |
White sibling pairs (Europeans) | essential hypertension | 6q27 | D6S281 | 190 | 3.2 | Caulfield et al., 2003 [20] |
SBP = Systolic blood pressure; DBP = diastolic blood pressure.
p value.