Table 4.

Risk factors for chronic GVHD among 1-year survivors

	Univariate		Multivariate
	HR (95% CI)	P	HR (95% CI)	P
Acute GVHD prophylaxis
Single agent	1.0
Multiple agents	1.47 (0.8-2.7)	.22
Buffy coat
No	1.0		1.0
Yes	2.13 (1.1-4.2)	.04	2.79 (1.3-5.8)	.01
Regimen
Cyclophosphamide	1.0
TBI, low (2-6 Gy)	1.18 (0.4-3.4)
TBI, high (10-12 Gy)	3.68 (1.7-8.1)	.02
Donor
Matched related	1.0		1.0
Mismatched related	5.36 (2.1-14)	.01	6.98 (2.6-19)	.004
Unrelated	1.53 (0.6-3.7)		1.98 (0.8-4.9)

CI indicates confidence interval; HR, hazard ratio; and TBI, total body irradiation.