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. 2011 Aug 8;6(8):e22386. doi: 10.1371/journal.pone.0022386

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Brégeon et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Heart rate (HR) and systolic arterial blood pressure (ABP) in animals ventilated at 25 cmH₂O airway pressure only (HV₂₅-sham), or associated with vagal stimulation (HV₂₅-stim) or a specific antagonist of the alpha7 nicotinic acetylcholine receptor, methyllycaconitine (MLA) (HV₂₅-stim/MLA), or without vagal stimulation but pre-treatment with the alpha7 nicotinic acetylcholine receptor agonist PNU (HV₂₅-PNU). *p<0.05, ** p<0.01; *** p<0.001 versus HV₂₅-sham.