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. 2011 Aug 8;6(8):e22934. doi: 10.1371/journal.pone.0022934

Figure 5. Quercetin suppressed p300 HAT activity.

Figure 5

(A), Human MDA-MB-231 and MCF7 cells were transfected with FLAG-p300 for 24 h and then treated with quercetin for 24 h. The p300 protein was isolated from nuclear extracts and HAT activity was measured. (B), MDA-MB-231 cells were transfected with FLAG-p300. The p300 protein was isolated from nuclear extracts and then treated with quercetin in vitro for 30 min. HAT activity was measured. Each bar represents mean ±SD of three experiments. *, P<0.05, significant differences between treatment groups and control groups.