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. 2011 Aug 8;6(8):e22841. doi: 10.1371/journal.pone.0022841

Figure 4. ROS production in macrophages from Ucp2−/−, iNos−/−, and (Ucp2-iNos)−/− deficient mice.

Figure 4

Peritoneal macrophages were obtained at day 10 after MOG immunization and stimulated in vitro with 500 ng/ml phorbol merystil acetate during 1 hour as described in Materials and Methods. Data represent mean ± SEM from 5–13 mice per strain. Student's t test was performed to determine the statistical significance of the differences between Ucp2−/−, iNos−/− and (Ucp2-iNos)−/− mice. *, P<0.05; **, P<0.01.