Table 1. Clinical parameters of the mice during Experimental Autoimmune Encephalomyelitis.
N1 | Mean clinical score | Mean day of onset | Incidence | Mortality | |||
(%) | (%) | ||||||
Vogler et al. | Day 13 | Day 14 | Day 15 | ||||
Ucp2+/+ | 25 | 1.7±0.2 | 11.5±0.8 | 75 | |||
Ucp2−/− | 40 | 2.9±0.2 | 13.0±0.6 | 75 | |||
This study | Day 13 | Day 14 | Day 15 | ||||
Ucp2+/+ | 18 | 1.1±0.2 | 1.4±0.2 | 1.4±0.2 | 11.9±0.7 | 90 | 16.6 |
Ucp2−/− | 17 | 1.4±0.3 | 2.3±0.4 | 2.5±0.4 | 11.8±0.6 | 89.4 | 17.6 |
iNos−/− | 17 | 2.9±0.5 | 3.4±0.5 | 3.5±0.5 | 10.5±0.6 | 94.4 | 29.4 |
(Ucp2-iNos)−/− | 17 | 1.4±0.4 | 1.7±0.4 | 2.4±0.5 | 13.5±0.3 | 89.5 | 17.6 |
N = number of mice; Data represent means ± SEM.