Table 3. Multivariate logistic regression analysis: association between adherence variables and failure.
Variable | Univariate OR(95% CI) | Mulitvariate OR (95% CI)* |
Cumulative adherence of <95% | 2.09 (0.93–4.70) | 1.69 (0.71–4.02) |
Cumulative adherence of <90% | 4.50 (1.31–15.48) | 3.01 (0.81–11.21) |
One episode of adherence variation of >10% | 2.07 (1.01–4.24) | 2.20 (1.04–4.64) |
≥1 episodes of treatment interruption (≥28 days) | 4.42 (1.67–11.70) | 4.01 (1.45–11.10) |
≥1 episodes of treatment interruption (≥28 days) not due to toxicity | 5.62 (1.76–17.97) | 3.90 (1.09–13.92) |
≥1 episodes of patient initiated treatment interruption (≥28 days) | 7.32 (1.30–41.14) | 4.40 (0.78–24.93) |
*Adjusted for age, sex, baseline CD4 count, baseline viral load.