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. 2011 Aug 8;6(8):e23088. doi: 10.1371/journal.pone.0023088

Table 3. Multivariate logistic regression analysis: association between adherence variables and failure.

Variable Univariate OR(95% CI) Mulitvariate OR (95% CI)*
Cumulative adherence of <95% 2.09 (0.93–4.70) 1.69 (0.71–4.02)
Cumulative adherence of <90% 4.50 (1.31–15.48) 3.01 (0.81–11.21)
One episode of adherence variation of >10% 2.07 (1.01–4.24) 2.20 (1.04–4.64)
≥1 episodes of treatment interruption (≥28 days) 4.42 (1.67–11.70) 4.01 (1.45–11.10)
≥1 episodes of treatment interruption (≥28 days) not due to toxicity 5.62 (1.76–17.97) 3.90 (1.09–13.92)
≥1 episodes of patient initiated treatment interruption (≥28 days) 7.32 (1.30–41.14) 4.40 (0.78–24.93)

*Adjusted for age, sex, baseline CD4 count, baseline viral load.