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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Neurochem Int. 2011 Mar 17;59(4):473–481. doi: 10.1016/j.neuint.2011.03.003

Figure 4.

Figure 4

Scheme of a hypothesized network of genes involved in nerve process elongation and synapse formation, genes whose expression is up-regulated in Glud1 Tg mice. Depicted in this scheme is the tip of a hypothetical growth cone and the genes involved in nerve process elongation and synapse formation. The genes were grouped based on their function: b1 - growth factor and ephrin receptors; b2 - glutamate receptor and scaffolding genes; b3 - extracellular matrix interacting genes (integrin); b4 - actin-organizing genes; b5 - focal adhesion complex genes; and b6 - signal transduction genes. Interactions among the genes shown are portrayed by lines connecting individual genes. Such interactions were culled from previously published studies. Only genes that were up-regulated in Glud1 as compared with wt mouse hippocampus and that are related to neurite growth and synapse formation are shown in this scheme. The figure is reproduced from Wang et al. BMC Genomics 2010, 11:360.