Table 4.
Spearman correlation coefficients obtained when the baseline value of each global index is used to predict the rate of change, with associated p-values in brackets. Values in bold were significantly different from the model that used MD to predict subsequent slope of MD (p<5%). The indices labeled ‘cap’ are calculated after pointwise sensitivities were capped at the age-corrected normal value.
| Participants with GON | Participants without GON | ||||
|---|---|---|---|---|---|
| Baseline Index: | Based on model from: | Correlation with slope of MD | Correlation with slope of same index | Correlation with slope of MD | Correlation with slope of same index |
| MD | 0.34 (p=0.02) | 0.34 (p=0.02) | 0.09 (p=0.55) | 0.09 (p=0.55) | |
| LMS | Linear-scaled mean | 0.45 (p<0.01) | 0.37 (p=0.01) | 0.21 (p=0.16) | 0.12 (p=0.45) |
| CountG | Garway-Heath | 0.41 (p<0.01) | 0.13 (p=0.37) | 0.25 (p=0.10) | −0.00 (p=1.00) |
| CountHa | Harwerth | 0.41 (p<0.01) | 0.32 (p=0.02) | 0.21 (p=0.16) | 0.13 (p=0.38) |
| LossHo | Hood | 0.35 (p=0.01) | 0.25 (p=0.08) | 0.09 (p=0.56) | −0.00 (p=0.98) |
| CountD | Drasdo | 0.42 (p<0.01) | 0.36 (p=0.01) | 0.18 (p=0.23) | 0.01 (p=0.97) |
| CountDA | Drasdo (age-corrected) | 0.32 (p=0.02) | 0.25 (p=0.08) | 0.10 (p=0.52) | −0.10 (p=0.52) |
| LMS (cap) | Linear-scaled mean | 0.40 (p<0.01) | 0.39 (p=0.01) | 0.24 (p=0.11) | 0.39 (p=0.01) |
| CountG (cap) | Garway-Heath | 0.32 (p=0.03) | 0.14 (p=0.32) | 0.27 (p=0.07) | 0.21 (p=0.16) |
| CountHa (cap) | Harwerth | 0.35 (p=0.02) | 0.31 (p=0.03) | 0.23 (p=0.13) | 0.39 (p=0.01) |
| LossHo (cap) | Hood | 0.43 (p<0.01) | 0.57 (p<0.01) | 0.05 (p=0.73) | 0.48 (p<0.01) |
| CountD (cap) | Drasdo | 0.30 (p=0.04) | 0.24 (p=0.10) | 0.09 (p=0.56) | −0.04 (p=0.81) |
| CountDA (cap) | Drasdo (age-corrected) | 0.38 (p=0.01) | 0.59 (p<0.01) | 0.12 (p=0.44) | 0.32 (p=0.03) |