Fig. 2.
Photomicrographs showing representative histology in proximal tibia in an ovary-intact control rat (A), an ovx + pair-fed rat (B), an ovx rAAV-GFP-treated rat (C), and an ovx rAAV-Lep-treated rat (D). Please note the low bone mass and high adiposity in the three ovx treatment groups compared to the ovary-intact group. See Tables 1 and 2 for quantitative changes in bone mass and architecture and Fig. 1 for changes in cellular endpoints.