Table 1.
Comparison of lesion volume measured by MRI and visible macroscopic imaging with 4 s of HIFU exposure. It is noted that at the concentration of 106 droplets/mL, copious ADV bubbles were observed, but no lesions were detected by either visible, macroscopic imaging or MRI, possibly due to the backscatter from the high-density ADV bubbles advancing the droplet vaporization proximally to shadow the focus.
| Droplet concentration (/mL) | MRI volume (cm3) | Optical volume (cm3) |
|---|---|---|
| 0 (n=8) | 0.05 ± 0.01 | 0.04 ± 0.01 |
| 104 (n=5) | 0.10 ± 0.01 | 0.12 ± 0.02 |
| 105 (n=8) | 0.29 ± 0.05 | 0.30 ± 0.05 |
| 106 (n = 8) | No lesion | No lesion |