Fig. 2.

Flow cytometry analysis of caspase-3 and CD95 expression. a Representation of a scatter plot defining a patient’s CD4+ and CD8+ populations on the left. The middle and right plots represent expression of activated caspase-3 and CD95 in a healthy control’s CD8+ T-cells (x-axis). b Flow cytometry dot plot showing a longitudinal expression of activated caspase-3 and CD95 in a chronic HCV-infected patient treated with the caspase-inhibitor GS-9450. The upper row depicts the caspase-3 expression while the lower row shows the CD95 expression (y-axis). From left to right, the study weeks 0, 2 and 7 are depicted