Table 2.

Outcome variables by treatment assignment

	PTX	Control	p
All subjects	(N = 10)	(N = 5)
Serious adverse events	2 (20%)	0 (0%)	0.52
Seizures during stay	4 (40%)	4 (80%)	0.28
Deaths	4 (40%)	1 (20%)	0.60
Time to death (hours)	35 (8 - 54)	10	-
Among survivors	(N = 6)	(N = 4)
Parasite clearance time (hours)	43 ± 9	31 ± 8	0.05
Fever resolution time (hours)	29 ± 17	17 ± 10	0.28
Coma resolution time (hours)*	8 (4 - 36)	8 (4 - 12)	0.69
Duration of hospitalization (days)	3 (3 - 17)	4 (3 - 15)	0.52
Neurological impairment after 72 hours	1 (17%)	2 (50%)	0.50
Neurological sequelae at 3 months	0 (0%)	1 (25%)	0.40

* Restricted to subjects with no neurologic impairment at 72 hours

Data are reported as N (%), mean ± standard deviation, or median (range)