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. 2011 May 3;152(7):2678–2689. doi: 10.1210/en.2010-1477

Fig. 1.

Fig. 1.

JunB-KO mice show strong growth retardation and increased death rate. A, Growth curve of JunB-KO (○) mice and WT littermates (■) (n = 10). Weight (grams) was measured at the age of 5, 10, 15, 20, 40, 80, and 100 d after birth. Statistical significance was determined using the two-tailed Student's t test. *, P < 0.05; **, P < 0.01. B, Survival rate of JunB-KO mice and WT littermates (n = 20, at the beginning of the experiment) on a chow diet from birth until the age of 12 wk. C, JunB-KO mice have strongly reduced fat mass, whereas lean body mass (percent body weight) was not changed in comparison with WT controls. BMC of JunB-KO mice and WT littermates (n = 7) was measured at the age of 100 d using the minispec live mouse analyzer (7.5 MHz) from Bruker. Statistical significance was determined using the two-tailed Student's t test. **, P < 0.01.