Fig. 2.
After BaCl2 injury, Pax7+ satellite cells and Tcf4+ fibroblasts expand rapidly in close proximity to one another and regenerating myofibers. (A-G,CC) MyHCemb+ regenerating myofibers. (H-N,DD,GG) Pax7+ satellite cells. (O-U,EE,HH) Tcf4+ muscle connective tissue (MCT) fibroblasts. (V-BB,FF) Sirius Red+ MCT. Arrows in I, P and Q label a few of the PHH3+ Pax7+ or PHH3+Tcf4+ cells. (II) Tibialis anterior (TA) cross-sectional area measured on Sirius Red-stained sections 30-40 μm from TA origin. At each time point, adjacent sections are shown. Scale bar: 100 μm for A-BB. For all graphs, mean ± s.e.m. are plotted.
