Figure 4.

Permeability as a function of applied volumetric strain (J). Since the raw data from stress relaxation testing do not provide the strain-dependent permeability directly, the intrinsic permeability (k₀) and strain-dependence parameter (M) were input to the constitutive model (Eq. 2) and plotted over a range of compressive stretch (λ). Permeability decreased with increasing compressive strain, but curves for ChABC treated tissues decreased more rapidly than those for the control tissues. Permeability was reduced to nearly zero for all treatment groups by 50% compressive strain (λ = 0.5).