Figure 7. Lipids mediate crystal contacts in bacteriorhodopsin and aquaporin-0.

In the starting 6Å resolution experimental map, the density for lipids was not visible. However, as the phases were extended and improved, the density for lipids became increasingly apparent. In the final σ_A-weight 2F_o-F_c map, the lipid densities were pronounced and matched the previously published structures of the membrane surrounding both bR and AQP0. bR and AQP0 are illustrated in blue and lipids in yellow.