Table 1.

List of genes containing SNPs with the largest effect sizes (P ≤ 10⁻⁵) estimated from GWAS and the P-values estimated from gene expression values in the Caucasian (EU), Asian and ER⁺ and ER⁻ (EU) populations.

Gene name (symbol)	SNP ID (rs-ID)	SNP (P-value)	EU (P-value)	Asian (P-value)	ER+/ER−(P-value)
ABCC4	rs1926657	1.9 × 10−6	0.04	0.4	0.07
CASP8	rs1045485	1.1 × 10−7	0.005	0.5	0.1
COL1A1	rs2075555	8.3 × 10−8	5.00E-06	0.0005	0.1
ECHDC1	rs6569480	6.1 × 10−8	1.00E-05	0.001	0.01
ECHDC1	rs7776136	6.6 × 10−8	1.00E-05	0.001	0.01
ESR1	rs3020314	8 × 10−5	0.7	0.0006	5.00E-06
FGFR2	rs2981582	2 × 10−76	5.00E-06	0.1	0.49
FGFR2	rs2981579	1.79 × 10−31	5.00E-06	0.1	0.49
FGFR2	rs2420946	3.5 × 10−6	5.00E-06	0.1	0.49
FGFR2	rs1219648	3.2 × 10−6	5.00E-06	0.1	0.49
FGFR2	rs1078806	1.5 × 10−5	5.00E-06	0.1	0.49
FBNI	rs1876206	6.0 × 10−6	0.6	0.2	0.03
GRIK1	rs458685	6.0 × 10−6	5.00E-06	0.7	0.02
LOC643714	rs3803662	1 × 10−36	1.00E-05	–	–
LSP1	rs3817198	3.0 × 10−9	0.6	0.1	0.01
PPP2R2B	rs9325024	1.7 × 10−5	0.4	0.9	0.8
RAD51L1	rs999737	1.74 × 10−7	0.5	0.1	8.00E-05
SLC4A7	rs4973768	4 × 10−23	0.8	0.1	0.6
STXBP4	rs6504950	1.4 × 10−8	0.7	–	–
TGFB1	rs1800470	2.8 × 10−5	0.0007	0.8	0.5
TOX3	rs12443621	2 × 10−19	0.0001	6.50E-05	7.00E-05
TOX3	rs3803662	5.9 × 10−19	0.0001	6.50E-05	7.00E-05
TOX3	rs8051542	1.0 × 10−36	0.0001	6.50E-05	7.00E-05
BTNL8	rs7711990	8.4 × 10−5	0.5	0.1	0.2
H19	rs2107425	2 × 10−5	0.2	–	–
MAP3K1	rs889312	4.6 × 10−20	0.04	0.9	0.01

Notes: EU indicates Caucasians, ER⁺ and ER⁻ indicate estrogen positive and negative, respectively,—indicates that the gene was not represented on the Chip, thus no estimate of P-values is available.