Table 1.
D. septosporum genes and their predicted gene products, with amino acid identities to A. nidulans (ST) and A. parasiticus (AF) gene products. Horizontal lines separate known mini-clusters. D. septosporum genes experimentally verified as dothistromin genes are in bold.
| Gene | Predicted Size (aa) | Putative Gene Product Function | ST Gene Ortholog | Identity aa (%) | AF Gene Ortholog | Identity aa (%) |
|---|---|---|---|---|---|---|
| dotA | 263 | Versicolorin reductase | stcU | 79.1 | aflM | 80.2 |
| dotB | 414 | Oxidase | stcC | 24.0 | ||
| dotC | 602 | MFS transporter | aflT | 31.2 | ||
| dotD | 322 | Thioesterase | stcA | 37.9 | aflC | 34.8 |
| pksA | 2399 | Polyketide synthase | stcA | 57.0 | aflC | 54.8 |
| cypA | 511 | Averufin monooxygenase | stcB | 59.8 | aflV | 59.3 |
| avfA | 301 | Oxidase | stcO | 43.7 | aflI | 47.8 |
| epoA | 420 | Epoxide hydrolase | ||||
| moxA | 626 | Monooxygenase | stcW | 59.0 | aflW | 55.1 |
| DS31 | 231 | Translation elongation factor | stcT | 41.1 | ||
| hexA | (321) | Fatty acid synthase (partial) | stcJ | 41.3 | aflA | 48.8 |
| hypC | 262 | Anthrone oxidase | stcM | 47.9 | hypC | 35.2 |
| vbsA | 643 | Versicolorin B synthase | stcN | 69.1 | aflK | 72.0 |
| norB | 392 | Norsolorinic acid reductase | stcV | 43.4 | aflF | 60.7 |