Table 2.

Advantages and disadvantages of different approaches to inhibit hemorrhagic venoms.

Approach for inhibition of hemorrhagic venom	Advantages	Disadvantages
Horse or sheep-derived polyclonal antivenins	Large-scale use	Adverse reaction or anaphylactic shock
	High efficacy	Economic and ethic problems
Sheep-derived antibody (CroFab)	Utilized	Economic and ethic problems
	High efficacy
	Less allergenic
Polyclonal antibodies purified from chicken egg yolks of immunized hens (developed for Bothrops sp. venoms)	Promising for the yield of antibody	Economic problems
	Probably less allergenic	Not utilized
		(protocols to be developed and efficacy tested)
Natural inhibitors	Probably less allergenic	Economic problems
		Not utilized (protocols to be developed)
Electric current treatment	Probably not allergenic	Not utilized nor recommended
	Applicable by a portable system	(lack of scientific basis)