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. 2010 Apr 8;2(4):632–648. doi: 10.3390/toxins2040632

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© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Average metabolic responses of two chambers of PC-12 cells exposed to (a) one 2 minute dose of 100 nM CTx (●) or (b) a ten minute dose of 5 nM CTx (●). The spike in oxygen at 58 minutes is the result of noise spike in one of the chambers. Cell necrosis is triggered near 300 minutes.