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Evaluation of evidence for the “prime suspects” in the etiology of EN and UTT.
| Evidences | AA | versus | OTA |
|---|---|---|---|
| Nephrotoxic | + | + | |
| Carcinogenic | + | + | |
| Clinical picture similarities with EN-UTT | +/- | +/- | |
| DNA-adducts | +? | + | |
| Field exposure evidences (food, urine, blood) | - | + | |
| Higher exposure in EN over non-EN | - | +/- | |
| Toxic levels | lack of evid. | + |
+ = yes; - = no; ? = under debate.
