Table 2.
CaSR Consensus Peptide Sequences Enriched by Different APS1 Patient Sera
| Consensus peptide (amino acid residues of CaSRa) | Number of APS1 patient sera enriching consensus peptide (%) | APS1 patient serum samples enriching consensus peptidec |
|---|---|---|
| HFGVAAKDQDLKSRPESVECIRYNFRGFR (41–69)b | 12/14 (86) | 2–7, 9–11, 13–15 |
| FVAQNKIDSLNLD (114–126) | 5/14 (36) | 2–4, 7, 15 |
| SRLLSNKNQFKSFLRTIPNDEHQAT (171–195) | 4/14 (29) | 6, 10, 13, 14 |
a
Amino acid residues are numbered according to CaSR peptide sequence with the ATG initiation codon as residue number 1.
b
The 41–69 peptide sequence was enriched by a serum sample from the single AHH patient.
c
Numbers refer to individual APS1 patients.