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. 2009 Oct 12;25(4):734–745. doi: 10.1359/jbmr.091016

Table 2.

Data for Hindlimb Suspension Animal Model Development: Table with Serum Data for Pure Control and HS (No Microdamage Induction)

Control (WB) Hindlimb suspension (HS)


Day 0 21 35 0 21 35
n 5 5 5 10 9 8
Osteocalcin, ng/mL Avg. 2.47 1.72 2.07 1.93 1.39 1.32*
SD 1.93 0.78 0.52 0.83 0.85 0.48
TRAP5b, U/L Avg. 0.77 0.94 0.88 0.85 1.16** 1.16**
SD 0.19 0.20 0.11 0.17 0.43 0.30

Serum TRACP5b (RatTRAP, SBA Sciences) and OCN (Rat Osteocalcin, BT-490, Biomedical Technologies) were measured by ELISA [absorbance measured at 450 nm (OCN) and 405 nm (TRACP5b)] in order to determine relative systemic expression of markers of bone resorption and formation, respectively.

*

p = .07 versus HS day 0.

**

p = .07 WB versus HS for that day.