Table 1. Diagnosis of Hyperglycemia in Pregnancy.
Threshold values for diagnosis of GDM or overt diabetes in pregnancy
Glucose measure | Glucose concentration threshold * |
Above threshold (%)
|
|
---|---|---|---|
mmol/l | mg/dl | Cumulative | |
FPG | 5.1 | 92 | 8.3 |
1-h plasma glucose | 10.0 | 180 | 14.0 |
2-h plasma glucose | 8.5 | 153 | 16.1† |
To diagnose overt in pregnancy
| |||
Measure of glycemia | Consensus threshold | ||
FPG‡ | ≥7.0 mmol/l (126 mg/dl) | ||
A1C‡ | ≥6.5% (DCCT/UKPDS standardized) | ||
Random plasma glucose | ≥11.1 mmol/l (200 mg/dl) + confirmation§ |
One or more of these values from a 75-g OGTT must be equaled or exceeded for the diagnosis of GDM.
In addition, 1.7% of participants in the initial cohort were unblinded because of FPG > 5.8 mmol/l (105 mg/dl) or 2-h OGTT values > 11.1 mmol/l (200 mg/dl), bringing the total to 17.8%.
One of these must be met to identify the patient as having overt diabetes in pregnancy.
If a random plasma glucose is the initial measure, the tentative diagnosis of overt diabetes in pregnancy should be confirmed by FPG or A1C using a DCCT/UKPDS-standardized assay.
Previously published
Metzger BE, Gabbe SG, Persson B, Buchanan TA, Catalano PA, Damm P, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care. Mar;33(3):676-82.