Table 3. Cost-effectiveness of diagnostic strategies for 1.5 million persons with suspected active TB in India.
Diagnostic Test | Cost (US$) | Additional TB Cases Treated | Additional False-Positive Cases Treated | Secondary Cases Averted | DALYs Averted | Incremental DALYs Averted | Incremental Cost per DALY Averted (US$) |
Performed alone, relative to no microbiological testing | |||||||
Sputum smear microscopy | 11.9 million | 44,000 | 36,000 | 443,000 | 623,000 | 623,000 | 19 |
anda-TB serology | 47.5 million | 58,000 | 157,000 | 411,000 | 520,000 | (Dominated) | (Dominated) |
Performed on smear-negative specimens only, relative to sputum smear alone | |||||||
MGIT culture | 27.6 million | 26,000 | 12,000 | 112,000 | 130,000 | 130,000 | 213 |
anda-TB serology | 39.0 million | 24,000 | 152,000 | 112,000 | 110,000 | (Dominated) | (Dominated) |