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Table 3. Cost-effectiveness of diagnostic strategies for 1.5 million persons with suspected active TB in India.

Diagnostic Test Cost (US$) Additional TB Cases Treated Additional False-Positive Cases Treated Secondary Cases Averted DALYs Averted Incremental DALYs Averted Incremental Cost per DALY Averted (US$)
Performed alone, relative to no microbiological testing
Sputum smear microscopy 11.9 million 44,000 36,000 443,000 623,000 623,000 19
anda-TB serology 47.5 million 58,000 157,000 411,000 520,000 (Dominated) (Dominated)
Performed on smear-negative specimens only, relative to sputum smear alone
MGIT culture 27.6 million 26,000 12,000 112,000 130,000 130,000 213
anda-TB serology 39.0 million 24,000 152,000 112,000 110,000 (Dominated) (Dominated)