Table 1. Antibacterial activity of asCATH1 and 2.
Bacteria | asCATH1 | MIC (µM) asCATH2 | LL-37 |
Y. ruckeri | >80 | >80 | 40–80 |
V. anguillarum | 5–10 | 10–20 | 0.63–1.25 |
E. coli (ATCC 25922) | 1.25–2.5 | 10–20 | 0.63–1.25 |
Bacteria were incubated with varying concentrations of cathelicidin peptides for 18 h before absorbance was read at 600 nm to determine bacterial growth. MIC values are shown as the range of concentrations which produced a 50% reduction in growth compared to a control without cathelicidin.