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. 2011 Aug 8;194(3):355–365. doi: 10.1083/jcb.201101100

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© 2011 Harvey and Leinwand

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 2. — Gross pathology associated with cardiomyopathies. Illustrations depicting (A) a healthy heart with normal wall thicknesses and chamber volumes and (B) hypertrophic cardiomyopathy. Asymmetric hypertrophy of the interventricular septum as well as the left ventricular posterior wall and apex is present. (C) Dilated cardiomyopathy. Thinning of the ventricular walls enlarges the interior dimensions of the ventricular chamber. The left and right atria are also enlarged due to impaired ventricular relaxation. (D) Left ventricular noncompaction. Trabeculated ventricular walls create a spongy appearance, prominent in the left ventricular wall. Ao, aorta; LA, left atrium; LV, left ventricle; RV, right ventricle.