Skip to main content
. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: J Neurosurg. 2011 Mar 18;115(1):116–123. doi: 10.3171/2011.2.JNS10784

Figure 2. Curcumin promotes hematoma resolution after collagenase-induced ICH.

Figure 2

(A) Mice were treated with placebo (left panels) or curcumin (150 mg/kg; right panels) at the time of ICH. At 24h, 48h, or 72h post-ICH, coronal brain sections were prepared and digitally captured. Each panel depicts serial brain sections from a single, representative mouse per group. (B) Determination of hematoma area (mm2) at 48h or 72h post-ICH. Hematoma size was estimated by calculating the area inside a region of interest, as detailed in the Materials and Methods section (C) Hematoma volume was quantified by determining the hemoglobin content of each hemisphere at 72h post-ICH. Data are expressed as mean ± SEM and were analyzed by t-test or One-Way ANOVA (n=8 mice/group) followed by Student Newman-Keul’s post-hoc test (**p<0.01, ***p<0.001).