Figure 6. Curcumin reduces BBB permeability after ICH.
Mice were administered curcumin (150 mg/kg) at the time of collagenase-induced ICH. Evans blue extravasation, a sensitive measure of BBB disruption, was assessed at (A) 6h or (B) 12h or (C) 24h post-ICH. Comparisons between treatments groups were done using a one-way ANOVA followed by Student Newman Keul’s post-hoc test (**p<0.01, ***p<0.001). Data are expressed as mean ± SEM from 10 mice/group.