Figure 7. Curcumin attenuates brain edema following ICH.
Mice were administered curcumin (150 mg/kg) at the time of collagenase-induced ICH. Brain water content, a measure of cerebral edema, was assessed in the ipsilateral and contralateral hemispheres at (A) 24h or (B) 72h following ICH. Comparisons within each hemisphere between different treatments groups were done using a one-way ANOVA followed by Student Newman Keul’s post-hoc test (*p<0.05, ***p<0.001). No significant differences were observed between groups in the contralateral hemispheres. Data are expressed as mean ± SEM from 10 mice/group.