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. Author manuscript; available in PMC: 2011 Aug 10.
Published in final edited form as: Am J Physiol Renal Physiol. 2005 Aug 16;289(6):F1185–F1192. doi: 10.1152/ajprenal.00455.2004

Fig. 5.

Fig. 5

A: Original recording of membrane capacitance in a single mouse juxtaglomerular cell from NKCC1+/+ (left) and NKCC1−/− mice (right). The pipette contained control internal solution and the cell was bathed in control external solution supplemented with furosemide (10−4M) at the time indicated by the arrow (see method section). B: Mean relative change of Cm for JG cells from NKCC1+/+ (left) and NKCC1−/− mice (right). C: Whole-cell currents were measured in response to 9 pulses from −150 mV to +90 mV in 30 mV steps for 200 ms from a holding potential of −30 mV. These pulses were applied before and after superfusion with furosemide (10−4M). Mean steady-state I-V curves from 5 independent experiments before (circle) and after (square) 20 minutes of capacitance measurements are given. * p<.05 vs. control.