Figure 1. Heteroplasmy at position 16093 detected in buccal but not blood samples in a dizygotic twin pair aged 63 at the time of the study by A) Linear array assay and B) confirmed by dye terminator sequencing.

Two probes signals, 16093 1 and 16093 2, were detected by linear array analysis in the buccal samples but not in the blood of this twin pair, corresponding to 16093 T and C. The relative amounts of the 16093 T and C differed between the twins in the buccal and are reflected both by the intensity of the probe signals (A) as well as the peak height ratio in the sequence chromatogram (B).