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. Author manuscript; available in PMC: 2011 Aug 10.
Published in final edited form as: Ann Neurol. 1992 May;31(5):488–494. doi: 10.1002/ana.410310505

Table 4.

Behavioral and EEG Characteristics of CRH-induced Seizures: Age Dependence

Age (days) Behavior Electrographic Correlates
5–6 JM; forepaw grooming and clonus; tonus; LOB Amygdala; semirhythmic spikes (4/6); fast activity (2/6)
8–10 JM; semirhythmic fore paw clonus (run); LOB Rhythmic slow wave or spike wave; rare cortical discharge
11–14 JM; grooming, scratching; “swimming”; LOB Amygdala rhythmic spike wave; rare H or cortex sharp waves
16–22 JM; grooming; rare LOB or “major” seizures Similar to 11- to 14-day-old group; higher voltage

EEG = electroencephalography, CRH = corticotropin-releasing hormone, JM = jaw myoclonus manifesting as vigorous, persistent, and unstoppable licking and chewing; LOB = loss of balance; H = hippocampus.