Table 4.
Age (days) | Behavior | Electrographic Correlates |
---|---|---|
5–6 | JM; forepaw grooming and clonus; tonus; LOB | Amygdala; semirhythmic spikes (4/6); fast activity (2/6) |
8–10 | JM; semirhythmic fore paw clonus (run); LOB | Rhythmic slow wave or spike wave; rare cortical discharge |
11–14 | JM; grooming, scratching; “swimming”; LOB | Amygdala rhythmic spike wave; rare H or cortex sharp waves |
16–22 | JM; grooming; rare LOB or “major” seizures | Similar to 11- to 14-day-old group; higher voltage |
EEG = electroencephalography, CRH = corticotropin-releasing hormone, JM = jaw myoclonus manifesting as vigorous, persistent, and unstoppable licking and chewing; LOB = loss of balance; H = hippocampus.