Table 1. Demographic and Clinical Characteristics of the Sample.
| Control subjects | UHR | FEP | Statistic | |
|---|---|---|---|---|
| Age (±SD) years | 21.83±4.47 | 19.56±3.46 | 23.44±4.93a | F[2,73]=3.60, p=0.03 |
| Gender (male/female) | 28/12 | 14/4 | 10/8 | Fisher's=2.09 NS |
| Education (±SD) years | 14.47±3.32 | 10.67±2.61b | 12.11±3.51b | F[2,73]=9.60, p<0.001 |
| Handedness (right/left) | 40/0 | 18/0 | 18/0 | NS |
| Length of illness (±SD) weeks | NA | 16.56±12.28 | 18.72±18.14 | NS |
| Tobacco (ever used) | 9/40 | 1/18 | 6/18 | Fisher's=4.32 NS |
| Cannabis (ever used) | 0/40 | 1/18 | 2/18 | Fisher's=6.12, p=0.03 |
| Use of antipsychotic treatment | 0/40 | 0/18 | 0/18 | NS |
| Use of SSRIs | 0/40 | 4/18 | 0/18 | Fisher's=9.26, p=0.005 |
| PANSS positive symptoms | 22.17±3.94 | |||
| PANSS negative symptoms | 26.72±6.87 | |||
| PANSS general symptoms | 51.44±15.23 | |||
| SIPS positive symptoms | 12.72±3.95 | |||
| SIPS negative symptoms | 17.94±5.73 | |||
| SIPS disorganization symptoms | 9.28 ±3.14 | |||
| SIPS general symptoms | 8.94±3.55 |
Abbreviations: NA, not applicable; NS, not significant; SSRIs, selective serotonin reuptake inhibitors.
Significant post hoc pair-wise comparisons with Bonferroni correction (p<0.05) are indicated: a vs UHR; bvs controls