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. 2011 May 4;36(9):1912–1920. doi: 10.1038/npp.2011.77

Figure 1.

Figure 1

Propranolol disrupts retrieval of a cocaine-associated conditioned place preference (CPP). Following conditioning with (a) 10 mg/kg or (b) 20 mg/kg doses of cocaine, propranolol but not saline injections (arrows) prevented rats from expressing a CPP for the previously cocaine-paired chamber over the previously saline-paired chamber during the first CPP trial. Propranolol- but not saline-treated rats continued to show no CPP during subsequent propranolol-free trials. ***p<0.001, **p<0.01, and *p<0.05.