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. 2011 Jul 20;17:2003–2010.

Table 1. Serum cytokine levels in patients with intermediate uveitis and in controls.

Inflammatory mediators Controls (n=10) IU patients (n=36) Active IU (n=15) Quiescent IU (n=21) CME (n=7) No CME (n=29) Systemic therapy (n=10) No systemic therapy (n=26) Systemic disease (n=9) No systemic disease (n=27)
Mean age (yrs)
 40
 36
 42
 32
 44
 35
 43
 36
 44
 34
Geometric mean (pg/ml)
Median (pg/ml)
Range (pg/ml)
p value
IL-1β (2.0)*
 4.0
4.8
2.0–6.8
 2.9
2.9
2.0–11.7
 2.8
3.2
2.0–11.7
 2.5
2.6
2.0–5.7
 1.8
1.1
2.0–4.4
 2.9
3.5
2.0–11.7
 1.9
3.2
2.2–6.7
 2.9
4.0
2.0–11.7
 1.5
1.1
2.0–4.5
 3.1
3.6
2.0–11.7
 
 0.053
 0.820
 0.110
 0.101
 0.127
IL-6 (0.5)
 3.6
3.3
2.6–8.1
 3.3
3.3
2.4–17.4
 4.0
3.4
2.6–17.4
 3.6
3.3
2.4–6.8
 4.8
4.0
3.1–17.4
 3.5
3.2
2.4–7.5
 4.1
4.0
2.7–7.5
 3.6
3.2
2.4–17.4
 4.3
4.0
3.1–6.8
 3.6
3.2
2.4–17.4
 
 0.990
 0.657
 0.121
 0.063
 0.693
IL-8 (0.4)
 8.6
8.7
2.3–33.3
 8.4
8.4
3.7–14.3
 8.3
8.5
4.6–13.4
 8.0
7.4
3.7–14.3
 8.5
8.4
6.1–11.5
 8.0
8.3
3.7–14.3
 8.7
8.9
4.6–14.3
 7.9
7.4
3.7–13.4
 9.0
9.1
6.8–11.5
 7.8
8.0
3.7–14.3
 
 0.783
 1.000
 0.930
 0.566
 0.180
IL-10 (1.5)
 2.5
2.3
1.5–9.9
 2.1
2.1
1.5–7.0
 2.2
2.3
1.5–7.0
 1.9
2.1
1.5–3.6
 2.6
2.9
1.5–7.0
 1.9
2.1
1.5–5.4
 2.5
2.4
1.5–7.0
 1.9
2.0
1.5–5.4
 1.7
1.9
1.5–2.9
 2.1
2.2
1.5–7.0
 
 0.286
 0.202
 0.065
 0.256
 0.192
TNF-α (2.0)
 1.6
1.3
2.0–3.2
 3.2
3.2
2.0–6.7
 2.8
2.8
2.0–6.7
 3.0
3.3
2.0–4.2
 3.0
3.1
2.5–4.2
 2.9
3.3
2.0–6.7
 2.5
2.9
2.0–6.7
 3.1
3.3
2.0–6.7
 2.7
3.1
2.0–3.3
 3.0
3.3
2.0–6.7
 
 <0.0001
 0.072
 0.387
 0.034
 0.157
IL-12p70 (1.5)
 1.9
2.2
1.5–2.7
 2.2
2.2
1.5–3.8
 1.8
2.2
1.5–3.7
 2.1
2.2
1.5–3.8
 1.4
2.2
1.5–3.2
 2.1
2.2
1.5–3.8
 1.5
1.5
1.5–3.8
 2.1
2.2
1.5–3.7
 1.7
1.9
1.5–3.5
 2.0
2.2
1.5–3.8
  0.990 0.401 0.206 0.135 0.349

*: lower detection limit for each cytokine (pg/ml). IU: intermediate uveitis; CME: cystoid macular edema.