Table 4.
ORs of erythema for different polymorphisms and their combination
| Polymorphisms | Genotype |
Percentage of ≥G1 |
OR (95% CI) |
Chi-squared p-value | Fisher's exact test p-value |
|---|---|---|---|---|---|
| XRCC1 Arg194Trp | (Aa/aa) | 8% | 1 | ||
| (AA) | 41% | 8.07 (1.02-373.8) | 0.026 | 0.042 | |
| XRCC3 Thr241Met | (Aa/aa) | 41% | 1 | ||
| (AA) | 17% | 0.29 (0.05-1.29) | 0.07 | 0.081 | |
| XRCC3 A4541G (5'UTR) | (aa) | 50% | 1 | ||
| (AA/Aa) | 33% | 0.49 (0.01-40.29) | 0.611 | 1 | |
| XRCC1Arg194Trp/GSTP1 | Others | 50% | 1 | ||
|
XRCC1(Aa/aa) or GSTP1 (Aa/aa) |
23% | 0.3 (0.08-1.08) | 0.034 | 0.046 | |
| XRCC1Arg194Trp/XRCC3 Thr241Met § | Others | 48% | 1 | ||
|
XRCC1 (Aa/aa) or XRCC3 (AA) |
15% | 0.2 (0.04-0.78) | 0.008 | 0.011 | |
| XRCC1 Arg194Trp/XRCC1 Arg399Gln | Others | 46% | 1 | ||
|
XRCC1 Arg194Trp (Aa/aa) or XRCC1 Arg399Gln (AA) |
24% | 0.39 (0.1-1.35) | 0.088 | 0.099 | |
| XRCC1 Arg194Trp/GSTA1 # | Others | 11% | 1 | ||
|
XRCC1 (Aa/aa) or GSTA1 (AA) |
44% | 6.01 (1.16-61.04) | 0.016 | 0.018 |
Abbreviations: OR = odds ratio; calculated to homozygous normal genotype; 95% CI = 95% confidence interval.
§ α = 0.05, 2-tailed power (1-β = 78%; α = 0.05, 1- tailed power > 80%
# α = 0.05, 2-tailed power (1-β = 75%; α = 0.05, 1- tailed power > 80%