Table 2. Comparative brain stem lesions on MRI in patients with ADEM, NMO, and MS.

	ADEM (n = 17)	NMO (n = 23)	MS (n = 25)	P	P1	P2	P3
Number of lesions	3(1–6)	1(1–5)	2(1–3)	<0.001	<0.001	<0.001	0.314
Sagittal section
Diameter, median, mm	10.0(8.0–26.0)	12.0(3.0–17.0)	8.0(5.0–17.0)	0.030	0.726	0.009	0.001
Midbrain, n (%)	16 (94.1)	4 (17.4)	10(40.0)	<0.001	<0.001	<0.001	0.085
Pons, n (%)	12 (70.6)	8 (34.8)	21 (84.0)	0.001	0.025	0.511	<0.001
Medulla, n (%)	6 (35.3)	21(91.3)	9 (36.0)	<0.001	<0.001	0.963	<0.001
Axial section
Ventral, n (%)	14 (82.4)	2 (8.7)	11(44.0)	<0.001	<0.001	0.013	0.006
Dorsal, n (%)	3 (17.6)	21 (91.3)	23 (56.0)	<0.001	<0.001	0.013	0.006
Well defined margins, n (%)	0	2 (8.7)	19 (76.0)	<0.001	0.499	<0.001	<0.001
Bilateral or symmetrical, n (%)	14 (82.4)	3 (13.0)	2 (8.0)	<0.001	<0.001	<0.001	0.572

Abbreviations: ADEM = acute disseminated encephalomyelitis; NMO = neuromyelitis optica; MS = multiple sclerosis; P = comparative three groups; P1 = ADEM vs NMO; P2 = ADEM vs MS; P3 = NMO vs MS.