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. 2011 Jul 28;204(2-3):118–126. doi: 10.1016/j.toxlet.2011.04.022

Fig. 2.

Fig. 2

AAI elevates whereas OTA diminishes VEGF production in LLC-PK1 cells. LLC-PK1 cells were transfected with reporter plasmid containing luciferase encoding sequence under the control of VEGF promoter and then stimulated with toxins. The elevation of VEGF promoter activity 24 h after AAI and diminishment after OTA delivery was observed (A). Analysis of mRNA level by real-time PCR (B) and protein production by ELISA (C) indicated the enhancement and down-regulation of VEGF expression after AAI and OTA adding, respectively. Mean of 3 experiments performed in duplicates; *p < 0.05 vs control.