Table 1.
Genes that are downregulated by pIas3 overexpression (but not by sTaT3 knockdown) using at least a 4-fold change as cutoff
| Symbol | Entrez gene name | Affymetrix/Entrez gene | Fold change |
| CDH8 | cadherin 8, type 2 | 217574_at | −25.99 |
| ATG16L1 | ATG16 autophagy related 16-like 1 (S. cerevisiae) | 220521_s_at | −22.63 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 213516_at | −21.11 |
| TAGLN | transgelin | 205547_s_at | −18.38 |
| GLRB | glycine receptor, β | 205280_at | −17.15 |
| IL32 | interleukin 32 | 203828_s_at | −17.15 |
| CEP135 | centrosomal protein 135 kDa | 207286_at | −14.93 |
| MMRN1 | multimerin 1 | 205612_at | −14.93 |
| HSPG2 | heparan sulfate proteoglycan 2 | 201654_s_at | −12.13 |
| KLHL4 | kelch-like 4 (Drosophila) | 214591_at | −12.13 |
| GOLGA4 | golgi autoantigen, golgin subfamily a, 4 | 215203_at | −9.85 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 200665_s_at | −9.85 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 205532_s_at | −9.19 |
| TCF4 | transcription factor 4 | 212385_at | −9.19 |
| C4BPB | complement component 4 binding protein, β | 208209_s_at | −8.57 |
| AOX1 | aldehyde oxidase 1 | 205082_s_at | −8 |
| LYPD1 | LY6/PLAUR domain containing 1 | 212909_at | −7.46 |
| MBD6 | methyl-CpG binding domain protein 6 | 214384_s_at | −7.46 |
| MTMR8 | myotubularin related protein 8 | 220537_at | −6.06 |
| NRG1 | neuregulin 1 | 208241_at | −5.66 |
| EPHA5 | EPH receptor A5 | 215664_s_at | −5.28 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 214753_at | −5.28 |
| DCLK1 | doublecortin-like kinase 1 | 205399_at | −4.92 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 204359_at | −4.92 |
| SGCD | sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) | 213543_at | −4.92 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 211453_s_at | −4.59 |
| MED13L | mediator complex subunit 13-like | 216109_at | −4.59 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 203370_s_at | −4.59 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 208337_s_at | −4.29 |
| PDGFC | platelet derived growth factor C | 218718_at | −4.29 |
| DIO2 | deiodinase, iodothyronine, type II | 203700_s_at | −4 |
| ETV1 | ets variant 1 | 221911_at | −4 |
| GLS | glutaminase | 203159_at | −4 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 205129_at | −4 |
| SMA4 | glucuronidase, beta pseudogene | 215599_at | −4 |
| TTLL3 | tubulin tyrosine ligase-like family, member 3 | 217818_s_at | −4 |