Table 2.
Genes that are upregulated by PIAS3 overexpression (but not STAT3 knockdown) using a 10-fold increase as cutoff
Symbol | Entrez gene name | Affymetrix/Entrez gene | Fold change |
APOL1 | apolipoprotein L, 1 | 209546_s_at | 11.31 |
AQP3 | aquaporin 3 (Gill blood group) | 39248_at | 12.13 |
CST1 | cystatin SN | 206224_at | 12.13 |
GBP1 | guanylate binding protein 1, interferon-inducible, 67 kDa | 202270_at | 12.13 |
IRF9 | interferon regulatory factor 9 | 203882_at | 12.13 |
SP110 | SP110 nuclear body protein | 208392_x_at | 12.13 |
TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 219360_s_at | 12.13 |
ANKRD26 | ankyrin repeat domain 26 | 205705_at | 13.00 |
TMOD2 | tropomodulin 2 (neuronal) | 219701_at | 13.00 |
C18ORF1 | chromosome 18 open reading frame 1 | 207996_s_at | 13.93 |
DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 218986_s_at | 13.93 |
FCGBP | Fc fragment of IgG binding protein | 203240_at | 13.93 |
IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 203596_s_at | 13.93 |
LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 220345_at | 13.93 |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 202340_x_at | 13.93 |
SAMD9 | sterile alpha motif domain containing 9 | 219691_at | 13.93 |
CCDC69 | coiled-coil domain containing 69 | 212886_at | 14.93 |
FAM63B | family with sequence similarity 63, member B | 37802_r_at | 14.93 |
PAQR6 | progestin and adipoQ receptor family member VI | 219236_at | 14.93 |
FGB | fibrinogen β chain | 204988_at | 16.00 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 217502_at | 16.00 |
PDE1A | phosphodiesterase 1A, calmodulin-dependent | 208396_s_at | 16.00 |
CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 206153_at | 17.15 |
IFI16 | interferon, gamma-inducible protein 16 | 208966_x_at | 17.15 |
S100P | S100 calcium binding protein P | 204351_at | 17.15 |
OASL | 2′-5′-oligoadenylate synthetase-like | 205660_at | 18.38 |
IRF7 | interferon regulatory factor 7 | 208436_s_at | 19.70 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 202688_at | 19.70 |
ESM1 | endothelial cell-specific molecule 1 | 208394_x_at | 21.11 |
FGA | fibrinogen alpha chain | 205649_s_at | 21.11 |
IGHM | immunoglobulin heavy constant mu | 216558_x_at | 21.11 |
NPHP1 | nephronophthisis 1 (juvenile) | 206285_at | 21.11 |
LAMP3 | lysosomal-associated membrane protein 3 | 205569_at | 22.63 |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 204932_at | 22.63 |
CES1 | carboxylesterase 1 (monocyte/macrophage serine esterase 1) | 209616_s_at | 24.25 |
PCSK5 | proprotein convertase subtilisin/kexin type 5 | 213652_at | 24.25 |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 209720_s_at | 25.99 |
HERC5 | hect domain and RLD 5 | 219863_at | 27.86 |
IFI6 | interferon, alpha-inducible protein 6 | 204415_at | 27.86 |
TRIM22 | tripartite motif-containing 22 | 213293_s_at | 27.86 |
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 218943_s_at | 29.86 |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 204747_at | 29.86 |
RSAD2 | radical S-adenosyl methionine domain containing 2 | 213797_at | 29.86 |
FXYD2 | FXYD domain containing ion transport regulator 2 | 217091_at | 34.30 |
TM4SF20 | transmembrane 4 L six family member 20 | 220639_at | 34.30 |
CDH17 | cadherin 17, LI cadherin (liver-intestine) | 209847_at | 36.76 |
MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 214303_x_at | 36.76 |
ISG20 | interferon stimulated exonuclease gene 20 kDa | 204698_at | 39.40 |
OAS2 | 2′-5′-oligoadenylate synthetase 2, 69/71 kDa | 204972_at | 39.40 |
IFIH1 | interferon induced with helicase C domain 1 | 219209_at | 42.22 |
IFI44 | interferon-induced protein 44 | 214453_s_at | 45.25 |
OAS1 | 2′,5′-oligoadenylate synthetase 1, 40/46 kDa | 205552_s_at | 45.25 |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 206385_s_at | 51.98 |
ISG15 | ISG15 ubiquitin-like modifier | 205483_s_at | 55.72 |
MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 202086_at | 55.72 |
CCL5 | chemokine (C-C motif) ligand 5 | 1405_i_at | 59.71 |
IFITM1 | interferon induced transmembrane protein 1 (9–27) | 201601_x_at | 90.51 |
IFI44L | interferon-induced protein 44-like | 204439_at | 103.97 |
BST2 | bone marrow stromal cell antigen 2 | 201641_at | 119.43 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 203153_at | 256.00 |
IFI27 | interferon, alpha-inducible protein 27 | 202411_at | 362.04 |