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CRH stimulation of WT and CRH KO mice. (a) Plasma ACTH concentration 30 minutes after either no injection (basal), or intraperitoneal injection of vehicle or 10 μg/kg CRH. AP < 0.005 vs. WT female CRH. (b) Plasma corticosterone concentration after CRH, vehicle, or no injection. BP < 0.05 vs. WT female vehicle; CP < 0.01 vs. WT female CRH; DP < 0.05 vs. WT male CRH.
