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Effects of sympathetic blockades on systolic BP and heart rate in 12-week-old transgenic skinny mice and nontransgenic littermates. Effect of bunazosin on systolic BP (a) and heart rate (b). Effect of hexamethonium on systolic BP (c) and heart rate (d). Effect of propranolol on systolic BP (e) and heart rate (f). AP < 0.05 and BP < 0.01 compared to the initial values.
