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. 2011 Aug 10;6(8):e23582. doi: 10.1371/journal.pone.0023582

Figure 7. Hydrogen bond formation between the platinum amines and adjacent bases in OX-TGGT DNA adducts.

Figure 7

Representative structure of OX-DNA in the TGGT sequence context that forms both the G7-O6 hydrogen bond and the T8-O4 hydrogen bond is shown using line representation (A) in PyMOL (www.pymol.org). The dach ligand, G6, G7 and A8 bases are shown using stick representation. The dach ligand, G6, G7 and A8 base-pairs of the same structure are shown in greater detail with the minor groove facing the reader (B) and along the side (C).