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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Apr 20;1824(1):207–223. doi: 10.1016/j.bbapap.2011.04.008

Figure 5.

Figure 5

Inhibitor binding in the active site of PMII. (A) Interactions of pepstatin A with PMII (PDB 1XDH). Pepstatin A is shown in ball-and-stick representation with the carbons colored green. Protein residues are shown as thinner sticks with carbons in gray and hydrogen bonds are marked with dashed lines. (B) Binding mode of one of the two achiral inhibitors found in the crystal structure 2BJU to the “flap pocket” of PMII. The inhibitor is shown in ball-and-stick model with the carbons colored green. Protein residues are shown as thinner sticks with carbons in gray.